Laser Assisted Hatching Treatment Centre


Laser Assisted Hatching Treatment Centre — KIC Delfinium, is a place where every fertility journey is seen as a story of hope, science, and precision. For many couples, the IVF journey can feel overwhelming, especially when embryos fail to implant even after multiple attempts. Our mission is to bridge that vital gap between fertilization and pregnancy with advanced fertility solutions that combine innovation, care, and expertise. At KIC Delfinium, we focus on giving every couple renewed confidence and a greater chance at achieving their dream of parenthood.

At KIC Delfinium, we use precision-based micromanipulation techniques to enhance embryo implantation and improve pregnancy outcomes.


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    Laser Assisted Hatching

    One of our most effective procedures at KIC Delfinium is Laser Assisted Hatching, a cutting-edge method that uses a focused laser beam to create a tiny opening in the embryo’s outer layer, helping it hatches naturally and attach to the uterine lining. This minimally invasive technique significantly enhances the chances of successful implantation, particularly for patients who have experienced previous IVF failures. As a trusted leader in reproductive medicine, KIC Delfinium combines advanced technology with compassionate, evidence-based care, ensuring every patient receives world-class medical excellence supported by empathy and trust.

    Understanding the Science Behind Laser Assisted Hatching

    To understand how Laser Assisted Hatching works, it helps to know what happens naturally during early embryo development.

    When an egg is fertilized by sperm, it becomes a zygote — the first stage of human life. As this zygote divides and grows, it forms a multi-cellular structure called a blastocyst, surrounded by a transparent shell known as the zona pellucida.

    The zona pellucida has several essential functions:

    • It protects the embryo during early development.
    • It prevents multiple sperm from fertilizing the same egg.
    • It helps the embryo travel safely through the fallopian tube toward the uterus.

    However, for implantation to occur, the embryo must “hatch” from this outer shell and attach itself to the uterine lining (endometrium). This natural hatching process usually happens around the fifth or sixth day after fertilization.

    Why Some Embryos Struggle to Hatch Naturally

    Certain factors can make the zona pellucida unusually thick or hard, which prevents the embryo from hatching. When that happens, even healthy embryos cannot implant successfully — leading to failed IVF cycles.

    Common causes include:

    • Advanced maternal age (especially women over 35)
    • The freezing and thawing process in frozen embryo transfer (which can harden the shell)
    • Sub-optimal embryo development
    • Elevated follicle-stimulating hormone (FSH) levels
    • Poor ovarian response
    • Multiple previous IVF failures

    Laser Assisted Hatching is a scientifically proven method that helps overcome these challenges by creating a microscopic opening in the zona pellucida, facilitating easier hatching and implantation.

    What is Laser Assisted Hatching (LAH)?

    Laser Assisted Hatching is an advanced laboratory procedure used alongside IVF to enhance embryo implantation rates. The technique involves using a highly focused laser beam to create a tiny, precise hole in the embryo’s outer shell (zona pellucida). This opening helps the embryo “hatch” and attach to the uterine wall more efficiently.

    Unlike older hatching methods that used mechanical or chemical means, LAH is completely non-contact, computer-guided, and remarkably safe. The laser offers unparalleled precision, ensuring that only the outer layer is thinned or opened while the inner embryonic cells remain unharmed.

    This procedure is performed by experienced embryologists under high-resolution microscopes within a sterile, temperature-controlled environment.

    ivf process

    Who Can Benefit from Laser Assisted Hatching?

    Not every IVF cycle requires assisted hatching. However, it can be highly beneficial in certain situations where the embryo’s natural ability to hatch may be compromised.

    You may be recommended Laser Assisted Hatching at KIC Delfinium if you fall under one or more of the following categories:

    • Women aged 35 and above: Aging eggs tend to develop thicker outer shells, making hatching more difficult.
    • Patients with repeated IVF failures: Couples who’ve experienced multiple unsuccessful IVF cycles may benefit from improved implantation through LAH.
    • Frozen-Thawed Embryos: The freezing process can sometimes harden the zona pellucida. LAH helps soften it for easier hatching.
    • Poor Embryo Quality: When embryos show slow development or irregular morphology, LAH can enhance implantation potential.
    • After Genetic Testing (PGT/PGD): If embryos have undergone biopsy for genetic screening, LAH assists re-expansion and implantation.
    • Thick Zona Pellucida: Some embryos naturally form tougher shells, and assisted hatching improves their ability to attach to the uterus.

    Your fertility specialist at KIC Delfinium will evaluate your medical and reproductive history before recommending LAH as part of your IVF treatment plan.

    Step-by-Step Process of Laser Assisted Hatching at KIC Delfinium

    At KIC Delfinium, every procedure follows stringent safety protocols and advanced embryology standards. The entire process of Laser Assisted Hatching integrates seamlessly with your IVF cycle.

    IVF Cycle Preparation

    The woman begins her IVF cycle with ovarian stimulation medications to produce multiple eggs. These eggs are retrieved from the ovaries using ultrasound-guided aspiration and fertilized with sperm in the laboratory. The fertilized eggs develop into embryos over the next few days.

    Embryo Culturing

    Once fertilization occurs, the embryos are cultured under optimal laboratory conditions for 3–6 days until they reach the blastocyst stage. Our embryologists closely monitor their development, assessing cell division, morphology, and growth rate.

    Selection of Embryos for Hatching

    Not all embryos need assisted hatching. Our specialists select only those with a visibly thick zona pellucida or where implantation difficulty is anticipated. The embryos are transferred into a specialized dish under the laser microscope for the procedure.


    Laser-Based Hatching

    The embryologist uses a computer-controlled diode laser to create a micro-opening (approximately 10–20 microns wide) in the zona pellucida. This is achieved by applying a rapid, heat-free laser pulse that vaporizes a minuscule section of the outer layer without affecting the inner blastomeres.
    The laser energy is so localized that the temperature of the embryo’s inner environment remains stable throughout the process. This precision makes LAH the safest method of assisted hatching in modern reproductive medicine.

    Embryo Transfer

    After the laser procedure, the embryos are carefully placed in a nutrient medium to stabilize before being transferred to the uterus. The embryo transfer is a simple, painless outpatient procedure that takes only a few minutes and does not require anesthesia.

    Post-Transfer Monitoring

    Following the transfer, the patient receives hormonal medications to support the uterine lining and facilitate implantation. A beta-hCG blood test is done 10–12 days later to confirm pregnancy. The entire process is tracked and supported by continuous follow-up care from our fertility team.


    How Laser Assisted Hatching Improves IVF Success

    The natural hatching process is critical because an embryo cannot implant until it breaks free from its shell. By enabling this step, LAH directly improves implantation chances.
    At KIC Delfinium, our experience shows that:
    • Women over 35 see a 20–30 percent increase in pregnancy rates after LAH.
    • Couples with prior IVF failures have higher implantation success.
    • Frozen-embryo transfer cycles benefit due to softened outer layers.
    The laser’s precision minimizes embryo handling time, preserves cell integrity, and increases the embryo’s ability to attach to the uterine wall.

    The Safety and Technology of Laser Assisted Hatching

    Safety is the cornerstone of every fertility treatment we offer. Our embryology lab at KIC Delfinium uses advanced, non-contact diode laser systems designed specifically for assisted hatching.

    Our Safety Protocols Include:

    • Temperature-Controlled Workstations: Maintaining constant conditions prevents embryo stress.
    • Real-Time Monitoring: Embryos are observed continuously during the laser procedure.
    • Digital Micromanipulation: Laser focus and depth are computer-guided for precision.
    • Zero Physical Contact: No instruments touch the embryo, eliminating mechanical risk.
    • International Standards: Procedures follow ESHRE and ASRM guidelines.

    These protocols ensure that the embryo remains safe, viable, and stable throughout the process.

    When Should You Consider Laser Assisted Hatching?

    Your fertility expert might recommend Laser Assisted Hatching if you’ve faced any of the following:

    • Two or more failed IVF cycles
    • Low implantation rates despite good-quality embryos
    • A history of poor embryo expansion
    • Advanced maternal age
    • Cryopreserved embryos scheduled for transfer
    • A thick zona pellucida observed under microscopic analysis

    At KIC Delfinium, no patient is advised this treatment unnecessarily. Each decision is evidence-based, ensuring ethical and personalized fertility care.

    Benefits of Laser Assisted Hatching

    • Improved Implantation Rates: Helps embryos successfully attach to the uterus.
    • Enhanced Pregnancy Outcomes: Particularly for older women or repeated IVF failures.
    • Safe and Controlled: Uses advanced non-contact laser technology.
    • Precise and Quick: Procedure takes only a few seconds per embryo.
    • Higher Success with Frozen Embryos: Overcomes hardening due to freezing.
    • No Physical Manipulation: Reduces mechanical stress on embryos.
    • Minimal Risk: No damage to genetic material or inner cells.

    Cost of Laser Assisted Hatching

    The cost of Laser Assisted Hatching varies depending on the IVF protocol, number of embryos treated, and whether fresh or frozen cycles are used.
    At KIC Delfinium, we believe in transparent pricing. Our packages generally include:
    • Consultation with fertility experts
    • Embryo evaluation and selection
    • Laser hatching procedure
    • Embryo culture and transfer
    • Post-treatment monitoring
    We also offer flexible payment options and financing assistance. To know the exact cost for your situation, schedule a consultation with our specialists.

    Pre- and Post-Procedure Care

    Before the Procedure

    • Maintain a healthy diet rich in antioxidants.
    • Avoid smoking and alcohol.
    • Manage stress through relaxation or yoga.
    • Follow prescribed fertility medications and injections precisely.

    After the Procedure

    • Take adequate rest for at least 24 hours post-transfer.
    • Avoid intense physical activity.
    • Continue progesterone support medications.
    • Attend scheduled follow-up visits for hormone tests and scans.

    At KIC Delfinium, every patient receives personalized post-treatment care instructions and emotional counseling to ensure a comfortable recovery.

    Why Choose KIC Delfinium for Laser Assisted Hatching

    • Expert Fertility Specialists: Led by highly experienced embryologists and reproductive endocrinologists.
    • State-of-the-Art Labs: Equipped with advanced laser hatching systems and air-filtered embryology suites.
    • High Success Rates: Proven outcomes for women with prior IVF failures.
    • Individualized Protocols: Each treatment tailored to your fertility profile.
    • Ethical and Transparent Care: Honest recommendations, clear communication, and full cost transparency.
    • Compassionate Support: Our counselors and nursing team provide continuous emotional and medical guidance.

    KIC Delfinium is more than a fertility clinic — it’s a trusted destination for comprehensive reproductive care, where every patient is treated like family.

    Get in Touch to Learn More About Laser-Assisted Hatching

    If you are considering IVF or Laser-Assisted Hatching as part of your fertility treatment plan, our team of fertility experts is here to guide you through the process. We offer personalized consultations to help determine whether LAH is the right option for your situation. Call us at +91 9599754455 or fill out the contact form below to schedule your consultation and take the next step toward achieving your dream of parenthood.


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      Frequently Asked Questions (FAQs)

      • 1. What is Laser Assisted Hatching?
      1. What is Laser Assisted Hatching?

      Laser Assisted Hatching (LAH) is an advanced IVF laboratory technique designed to enhance the embryo’s ability to implant into the uterus. During IVF, the embryo is surrounded by a protective layer called the zona pellucida. In this procedure, a precise laser creates a small opening in this layer, allowing the embryo to hatch and attach more easily to the uterine wall. It improves the chances of successful implantation, especially in cases of previous IVF failures or advanced maternal age.


      • 2. Who needs Laser Assisted Hatching?
      2. Who needs Laser Assisted Hatching?

      Laser Assisted Hatching is typically recommended for women over the age of 35, those with thick zona pellucida, or patients who have had repeated unsuccessful IVF cycles. It can also benefit couples using frozen-thawed embryos or embryos with slower development. The technique helps embryos that may otherwise struggle to break out of their shell naturally, increasing their ability to implant successfully. Fertility experts suggest this method after evaluating medical history and previous IVF outcomes.


      • 3. Is Laser Assisted Hatching safe?
      3. Is Laser Assisted Hatching safe?

      Yes, Laser Assisted Hatching is a safe and well-established procedure performed by trained embryologists under controlled laboratory conditions. The laser used is extremely precise, minimizing any risk to the embryo. Unlike older mechanical or chemical hatching methods, the laser technique avoids direct contact, ensuring the embryo’s integrity. The procedure is quick, non-invasive, and proven to have no adverse effects on the embryo’s development. When done by experts, it significantly improves the chances of implantation without compromising safety.


      • 4. Can frozen embryos undergo Laser Assisted Hatching?
      4. Can frozen embryos undergo Laser Assisted Hatching?

      Absolutely. Laser Assisted Hatching is often performed on frozen-thawed embryos, as the freezing process can slightly harden the outer layer (zona pellucida), making it difficult for embryos to hatch naturally. By creating a tiny opening using the laser, embryologists assist these embryos in breaking through and attaching to the uterine lining more effectively. This technique has shown improved success rates in frozen embryo transfer (FET) cycles and is widely recommended for enhancing implantation outcomes.


      • 5. Does Laser Assisted Hatching help improve conception rates?
      5. Does Laser Assisted Hatching help improve conception rates?

      Yes, Laser Assisted Hatching has been shown to improve implantation and pregnancy rates in certain groups of patients. By gently thinning or opening the zona pellucida, it helps embryos implant more efficiently into the uterine wall. This can be particularly beneficial for women of advanced maternal age, those with poor embryo quality, or couples with repeated IVF failures. While it doesn’t guarantee pregnancy, it enhances the probability of successful embryo attachment and overall IVF outcomes.


      • 6. When is Laser Assisted Hatching performed during IVF?
      6. When is Laser Assisted Hatching performed during IVF?

      Laser Assisted Hatching is carried out just before the embryo transfer stage of the IVF process, typically on Day 3 or Day 5 of embryo development. At this point, embryologists use a micromanipulation system to create a tiny hole in the zona pellucida. The timing is crucial, ensuring the embryo is strong enough for transfer but not yet hatched. This careful procedure ensures better synchronization between the embryo’s readiness and the uterine environment for implantation.


      • 7. Is anesthesia needed for Laser Assisted Hatching?
      7. Is anesthesia needed for Laser Assisted Hatching?

      No anesthesia is required for Laser Assisted Hatching since it is performed entirely in the IVF laboratory before the embryo transfer. The procedure involves only the embryo, not the patient directly. It is completely painless, non-invasive, and completed in a matter of minutes. Patients won’t feel or experience any discomfort, as the embryo manipulation happens under the microscope using advanced laser technology. It’s a safe and comfortable step within the IVF cycle.


      • 8. How long does Laser Assisted Hatching take?
      8. How long does Laser Assisted Hatching take?

      Laser Assisted Hatching is a very quick procedure, usually taking only a few minutes per embryo. The process is performed by an embryologist using a high-precision laser under a microscope. Because of its speed and accuracy, the embryo remains in optimal conditions throughout. Despite its brief duration, this small step can have a meaningful impact on implantation success. It’s one of the simplest yet most effective add-on techniques in modern assisted reproductive technology (ART).


      • 9. Are there any risks involved in Laser Assisted Hatching?
      9. Are there any risks involved in Laser Assisted Hatching?

      The risks associated with Laser Assisted Hatching are minimal when performed by skilled embryologists. Since the laser precisely targets the zona pellucida and not the inner cells, the risk of harming the embryo is extremely low. Occasionally, there may be a slight chance of over-thinning the outer shell, but this is rare. The procedure has been proven safe and effective in thousands of IVF cycles worldwide and is considered a reliable method for improving implantation potential.


      • 10. Does Laser Assisted Hatching damage embryos?
      10. Does Laser Assisted Hatching damage embryos?

      No, Laser Assisted Hatching does not harm embryos when performed correctly in a controlled IVF lab setting. The laser used is highly focused and non-contact, meaning it doesn’t physically touch the embryo. It simply creates a tiny, precise opening in the outer shell. The embryo remains viable and healthy, continuing its normal development. Embryologists continuously monitor the embryo’s integrity during and after the procedure, ensuring its safety before transferring it into the uterus.





      • 11. How does Laser Assisted Hatching differ from natural hatching?
      11. How does Laser Assisted Hatching differ from natural hatching?

      In natural conception, embryos break out of their outer shell (zona pellucida) on their own before implanting in the uterus. In IVF, some embryos may struggle to hatch due to age, quality, or freezing. Laser Assisted Hatching replicates this process using advanced technology to gently assist the embryo in hatching. This ensures better chances of implantation, especially for older patients or frozen embryos. It mimics natural processes but with precision and control for higher success rates.


      • 12. Does every IVF patient need Laser Assisted Hatching?
      12. Does every IVF patient need Laser Assisted Hatching?

      Not every IVF patient requires Laser Assisted Hatching. It is generally advised for couples who’ve had repeated failed IVF attempts, older women, or cases involving frozen embryos. For younger patients with healthy embryos and no implantation issues, it may not be necessary. Fertility specialists determine the need based on the individual’s reproductive history, embryo quality, and lab findings. The goal is to personalize treatment for the best possible pregnancy outcomes without unnecessary interventions.


      • 13. Can Laser Assisted Hatching be combined with other IVF techniques?
      13. Can Laser Assisted Hatching be combined with other IVF techniques?

      Yes, Laser Assisted Hatching can be safely combined with other IVF techniques like Intracytoplasmic Sperm Injection (ICSI), Preimplantation Genetic Testing (PGT), or Frozen Embryo Transfer (FET). It complements these methods by enhancing embryo implantation potential. When used alongside such technologies, it provides a comprehensive approach to overcoming infertility challenges. Fertility experts assess each case individually to determine the right combination of treatments, ensuring both effectiveness and safety for achieving successful conception.


      • 14. Is Laser Assisted Hatching recommended for older women?
      14. Is Laser Assisted Hatching recommended for older women?

      Yes, women over 35 are often recommended Laser Assisted Hatching, as age-related changes can thicken the zona pellucida, making it difficult for embryos to hatch naturally. The laser technique helps overcome this barrier, improving implantation chances. For older women or those with diminished ovarian reserve, this method provides additional support during IVF treatment. It’s a gentle, non-invasive procedure that gives embryos the extra assistance they need for successful attachment to the uterine lining.


      • 15. How successful is Laser Assisted Hatching?
      15. How successful is Laser Assisted Hatching?

      The success of Laser Assisted Hatching depends on various factors such as embryo quality, maternal age, and underlying fertility issues. Studies have shown that it can improve implantation and pregnancy rates by 10–25% in selected cases. It’s most effective for women over 35 or couples with multiple failed IVF attempts. While results vary, many fertility centres report consistently higher success rates with this technique, particularly when performed by experienced embryologists using advanced laser systems.


      • 16. Does Laser Assisted Hatching increase the chance of twins or multiples?
      16. Does Laser Assisted Hatching increase the chance of twins or multiples?

      Laser Assisted Hatching itself does not directly cause multiple pregnancies. The likelihood of twins or triplets depends on the number of embryos transferred during IVF, not the hatching procedure. However, since the technique can improve implantation efficiency, transferring multiple embryos may slightly raise the chances of twins. Fertility specialists usually recommend transferring one or two embryos at most to balance success rates with safety and avoid high-risk multiple pregnancies.


      • 17. How does Laser Assisted Hatching improve implantation rates?
      17. How does Laser Assisted Hatching improve implantation rates?

      Laser Assisted Hatching helps embryos attach more easily to the uterine wall by creating a small opening in the zona pellucida. This allows the embryo’s inner cells to interact directly with the endometrial lining, promoting implantation. For patients with previous IVF failures or hardened embryo shells due to freezing, this step is crucial. It enhances the embryo’s natural hatching process, increases uterine receptivity, and ultimately boosts implantation success without affecting embryo health.


      • 18. Is Laser Assisted Hatching a mandatory part of IVF?
      18. Is Laser Assisted Hatching a mandatory part of IVF?

      No, Laser Assisted Hatching is an optional add-on treatment within the IVF process. It’s not required for every patient but can be beneficial in specific cases where embryos face difficulty implanting. Fertility specialists recommend it based on individual factors such as maternal age, embryo quality, and prior IVF outcomes. The procedure is entirely elective and used only when it can genuinely improve success rates without adding unnecessary interventions or risks.


      • 19. Can Laser Assisted Hatching be done for donor embryos?
      19. Can Laser Assisted Hatching be done for donor embryos?

      Yes, Laser Assisted Hatching can also be performed on donor embryos if required. Even though donor eggs or embryos are typically of high quality, certain factors like freezing and thawing can harden the zona pellucida. In such situations, performing LAH before transfer can enhance implantation potential. The decision depends on the embryo’s condition and the recipient’s uterine factors. The procedure remains equally safe and effective for donor-based IVF treatments.


      • 20. What is the cost of Laser Assisted Hatching?
      20. What is the cost of Laser Assisted Hatching?

      The cost of Laser Assisted Hatching varies depending on the IVF centre, the number of embryos treated, and whether it’s combined with other procedures like ICSI or PGT. Generally, it’s a relatively affordable add-on compared to the overall IVF cost. Most clinics offer transparent pricing and package options to make the procedure accessible. Considering its potential to increase pregnancy success rates, many couples find it a worthwhile investment during IVF treatment.

      Disclaimer

      As per ICMR and PCPNDT Guidelines No Pre Natal Sex Determination is done at KIC Delfinium Fertility Centre. As per ICMR and PCPNDT Guidelines Genetic Counselling can only be done in person.

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      KIC Delfinium Fertility Centre

      F-21, South Ex, Part 1, New Delhi 110049

      +91 9599754455

      Info@kicdelfinium.com

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