Platelet-Rich Plasma (PRP) for Fertility Treatment

At KIC Delfinium, we offer advanced fertility-enhancing treatments designed to support your parenthood journey with safety and precision. Platelet-Rich Plasma (PRP) Therapy is one such innovative approach that utilizes your body’s own healing components to improve reproductive health. During the procedure, a small sample of your blood is drawn, processed to concentrate the platelets, and then carefully injected into the targeted reproductive tissues. This rejuvenates the ovaries, enhances egg quality, and promotes endometrial growth, leading to improved chances of embryo implantation. With minimal discomfort and no major side effects, PRP therapy offers women a natural, effective, and science-backed fertility solution.

PRP therapy has been shown to be effective in addressing two common fertility issues: poor ovarian reserve and thin or damaged endometrium. Here’s how PRP therapy works for both:

1. Poor Ovarian Reserve (Diminished Egg Quantity and Quality)

As women age, the number of eggs in the ovaries naturally declines, and the quality of those eggs also deteriorates. However, some women experience premature ovarian aging, which can cause an early decline in ovarian reserve and make conception more challenging. In such cases, IVF treatment often becomes the primary option, but low ovarian reserve can lead to poor response to stimulation and low-quality eggs.

PRP therapy for ovarian rejuvenation works by increasing blood flow to the ovaries and stimulating dormant follicles to become active again. By injecting PRP into the ovaries, the growth factors in the plasma help stimulate follicular development, leading to better egg quality and quantity.

At KIC Delfinium Fertility Centre, we have seen promising results in women with poor ovarian reserve, giving them renewed hope of producing healthy eggs, even as they approach advanced maternal age.

2. Thin or Damaged Endometrium (Uterine Lining Issues)

The endometrium, or uterine lining, plays a crucial role in the success of an IVF pregnancy. For embryo implantation to occur, the endometrial lining needs to be thick and receptive. Thin or damaged endometrial lining is a common cause of implantation failure and can be caused by various factors, such as Asherman’s syndrome, chronic endometritis, or hormonal imbalances.

PRP therapy can help by stimulating the regeneration of the endometrial tissue. When PRP is injected into the uterine lining, it encourages the growth of new blood vessels (angiogenesis) and promotes the thickening of the endometrium. This process helps improve the chances of embryo implantation, especially for women who have experienced repeated IVF failures due to endometrial issues.

Steps Involved in Platelet-Rich Plasma (PRP) Therapy for Fertility Treatment

PRP therapy for fertility is a minimally invasive procedure that is performed in a clinical setting under local anaesthesia. Here’s a detailed look at the steps involved:

Step 1: Blood Collection

PRP therapy begins with the collection of a small amount of the patient’s blood (about 10–20 mL). The blood is drawn from a vein in your arm, similar to any standard blood test. This step takes only a few minutes.

Step 2: Processing the Blood to Concentrate the Platelets

The collected blood is then placed in a centrifuge—a machine that spins the blood at a high speed to separate the different components. The platelets, which are concentrated in the plasma, are separated from the red blood cells and other components of the blood. The resulting Platelet-Rich Plasma (PRP) contains a higher concentration of platelets than normal blood, making it ideal for tissue regeneration.

Step 3: Injection of PRP into the Target Area

Once the PRP is processed, it is injected into the target areas that need rejuvenation. There are two common applications in fertility treatments:

• Ovarian Rejuvenation: PRP is injected directly into the ovaries under ultrasound guidance. The platelets stimulate dormant follicles, which may improve egg quality and quantity in women with poor ovarian reserve. This step is usually done during the ovarian stimulation phase of IVF treatment.
• Endometrial Rejuvenation: PRP is injected into the uterine lining (endometrium) to encourage tissue repair and increase blood flow. This is especially useful for women with thin or damaged endometrial linings that affect embryo implantation.

Step 4: Monitoring and Follow-Up

After the PRP injections, the patient is closely monitored to ensure that there are no complications or side effects. For ovarian rejuvenation, ultrasound monitoring is used to check follicular development during the IVF cycle. For endometrial rejuvenation, ultrasound measurements of the endometrial thickness are taken to determine if the lining is responding to the treatment.

Step 5: IVF or Embryo Transfer

Following PRP therapy, patients proceed with IVF (or natural conception in certain cases) depending on their fertility treatment plan. The IVF process includes egg retrieval, fertilization, and embryo culture. For women undergoing PRP for endometrial issues, the embryo transfer is timed to ensure the endometrium is at its optimal thickness and receptivity.

While Platelet-Rich Plasma (PRP) Therapy is still considered experimental in fertility treatment, many women have experienced promising results. Here’s what you can generally expect:

• Ovarian Rejuvenation Results:
  PRP therapy may help stimulate follicular activity, leading to better egg quality and improved ovarian response to stimulation in women with low ovarian reserve.
• Endometrial Regeneration Results:
  In women with thin endometrial linings, PRP injections can improve blood flow and tissue repair, leading to a thicker, more receptive endometrium, which is crucial for successful implantation.
• Alternative to Egg Donation or Surrogacy:
  For women with poor ovarian reserve or endometrial issues, PRP therapy offers an alternative to egg donation or surrogacy, providing hope that they can conceive using their own eggs and uterus.

Results You Can Expect:

While PRP therapy has shown promise, the results can vary from patient to patient. Some women experience significant improvement, while others may not see much change. It’s important to have realistic expectations and understand that PRP therapy is not a guarantee. It should be viewed as part of a broader fertility treatment plan.

PRP therapy is a low-risk, minimally invasive procedure, as it uses your own blood (autologous treatment). This eliminates the risk of allergic reactions or infections that are common with external treatments.

You may be a good candidate for PRP therapy if:

• You have poor ovarian reserve but wish to conceive using your own eggs.
• You have a thin or damaged endometrial lining that affects embryo implantation.
• You have had repeated IVF failures and are looking for an alternative solution.

At KIC Delfinium, we take an individualized approach to fertility care. PRP therapy may be recommended as part of your personalized fertility treatment plan if you meet the criteria outlined above.

PRP therapy offers several key benefits for women facing fertility challenges:

1. Enhanced Ovarian Function and Egg Quality

For women with low ovarian reserve, PRP therapy can stimulate follicular development and potentially lead to better-quality eggs, increasing the chances of a successful IVF cycle.

2. Improved Endometrial Receptivity

For women with thin or damaged endometrial linings, PRP injections can thicken the endometrial lining, making it more receptive to embryo implantation and improving the chances of a successful pregnancy.

3. Reduced Risk of Egg Donation or Surrogacy

PRP therapy offers a non-invasive alternative to egg donation or surrogacy for women who wish to conceive using their own eggs and uterus.

4. Low-Risk, Autologous Procedure

Since PRP uses the patient’s own blood, there is no risk of immune rejection or allergic reactions, making it a safe and low-risk procedure for most women.

5. Enhances IVF Success Rates

By improving both ovarian function and endometrial health, PRP therapy can increase the chances of successful embryo implantation and a healthy pregnancy, improving the overall IVF success rates.

While PRP therapy is generally safe, it’s essential to be aware of the potential risks and considerations:

1. Limited Scientific Evidence

Although early studies show promising results, PRP therapy for fertility is still experimental. It is not a guaranteed solution, and results vary from patient to patient.

2. Not Suitable for All Fertility Issues

PRP therapy may not be appropriate for women with certain fertility conditions, such as severe uterine scarring or complete ovarian failure. A thorough consultation and assessment are essential to determine if PRP is right for you.

3. Possible Side Effects

Some women may experience mild discomfort, bruising, or swelling at the injection sites. However, these effects are typically temporary and resolve within a few days.

At KIC Delfinium Fertility Centre, we are committed to providing state-of-the-art fertility treatments with a personalized approach. Here’s why we are the right choice for your PRP for fertility treatment:

1. Experienced Fertility Specialists

Our team of fertility experts is highly trained and experienced in the latest fertility treatments, including PRP therapy. We are dedicated to providing the best care possible, tailored to your specific needs.

2. Advanced Laboratory Facilities

We have cutting-edge IVF laboratories and ultrasound guidance for precise PRP administration, ensuring optimal results for ovarian rejuvenation and endometrial repair.

3. Comprehensive Fertility Care

At KIC Delfinium, we offer comprehensive fertility services, including IVF, ICSI, egg freezing, and genetic testing. We integrate PRP therapy into your customized treatment plan to maximize your chances of success.

4. Personalized Treatment Plans

We understand that each fertility journey is unique. Our fertility experts create individualized plans that combine PRP therapy with other fertility treatments to give you the best chance of success.

5. High Success Rates

Our patients benefit from high success rates due to our advanced techniques and patient-centered care. We are committed to achieving the best outcomes for you.